Tīmeklis2011. gada 17. marts · BACKGROUND AND PURPOSE It is well established that cytochrome P450 2J (CYP2J) enzymes are expressed preferentially in the heart, and that ebastine is a substrate for CYP2J, but it is not known whether ebastine is metabolized in myocardium. Therefore, we investigated its pharmacokinetics in the … TīmeklisEffect of Dopamine D3 Antagonists on PPI in DBA/2J Mice or PPI Deficit Induced by Neonatal Ventral Hippocampal Lesions in Rats Kathy Kohlhaas Liliane Unger 2006, Neuropsychopharmacology
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TīmeklisRESEARCH PAPER bph_1338 1733..1739 Myocardial pharmacokinetics of ebastine, a substrate for cytochrome P450 2J, in rat isolated heart W Kang1, S Elitzer2, K Noh1, T Bednarek2 and M Weiss2 1College of Pharmacy, Yeungnam University, Kyoungbuk, South Korea, and 2Section of Pharmacokinetics, Department of Pharmacology, … Tīmeklis2003. gada 1. sept. · Rats were submitted to SMR by hind limb immobilization for 16 h / day from birth to postnatal day 28 (PND28). In situ isometric contractile properties of soleus muscle, fiber cross sectional area ... pictish triskelion
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