Human circular rna database
Web12 Apr 2024 · A circular RNA from the ZFR gene (CircZFR) inhibited gastric cancer (GC) cell propagation, cell cycle, and promoted apoptosis by sponging miR-107/miR-130a, involved in cell propagation and impeded apoptosis through targeting PTEN (T. Liu et al., 2024). PTEN is the most important negative regulator of the PI3K signaling pathway and … WebThe expression level of hsa_circ_0000711 in 101 paired CRC tissues and 3 CRC cell lines (HCT116, COLO205, and H-T29), as well as human normal colon epithelial cell line NCM460, were measured by quantitative real-time polymerase chain reaction.
Human circular rna database
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Web1 Jan 2024 · CircFunBase: a database for functional circular RNAs Increasing evidence reveals that circular RNAs (circRNAs) are widespread in eukaryotes and play important roles in diverse biological processes. However, a comprehensive functionally annotated circRNA database is still lacking. Web13 Apr 2024 · Novel RNA constructs to amplify RNA expression (e.g., self-amplifying RNA, circular RNA), modify translation (e.g., miRNA, siRNA), and gene editing (Cas9 mRNA, single guide RNA [sgRNA]) hold promise for next-generation cancer immunotherapy. Targeted delivery vehicles, including lipid and polymer nanoparticles, cell or extracellular …
WebThis was in accordance with the ciRS-7 (circular RNA sponge for miR-7) findings. 1 These data indicate that circRNA_100782 may activate IL6R and STAT3 by binding to miR-124 and inhibiting miR-124 activity. Next, we investigated whether the IL6-JAK2-STAT3 signaling pathway was responsible for BxPC3 cell proliferation. Web17 Jun 2024 · We identified 13 pre-existing circRNA databases 23, and most (99%) of the RNA Atlas circRNAs were annotated in at least one circRNA database (only 446 …
WebCircular RNAs (circRNAs) represent a new type of regulatory RNA which forms a covalently closed continuous loop from back-splicing events, a process in which the downstream 5' … Web16 Mar 2024 · Initially, RNA-seq algorithms were inefficient in distinguishing back-splicing junctions from the corresponding circular structures.However, advances in high-throughput RNA sequencing have led to the rapid establishment of circRNA databases.These databases facilitate in-depth research to elucidate the biological functions of circRNAs as …
Web20 Jul 2024 · TSCD is a tissue-specific circRNA database from RNA sequencing (RNA-seq) datasets and characterized the features of circRNAs in human and mouse 24. CSCD …
WebIn molecular biology, Circular RNAs (circRNAs) refer to a class of circular RNA molecules found across all kingdoms of life. [1] [2] [3] Studies in 2013 have suggested that circRNAs play important regulatory roles in miRNA activity. how many calories in one pump starbucks syrupWeb14 Apr 2024 · Circular RNAs (circRNAs), which are produced post-splicing of pre-mRNAs, are strongly linked to the emergence of several tumor types. The initial stage in conducting follow-up studies involves identifying circRNAs. Currently, animals are the primary target of most established circRNA recognition technologies. However, the sequence features of … how many calories in one plain bagelWeb11 Oct 2016 · In this study we established a circRNA database, named as circRNADb, containing 32,914 human exonic circRNAs carefully selected from diversified sources. … high rise opsWebProvide four interactome tools: RIscoper, IntaRNA, PRIdictor, DeepBind. Add the RNA editing/localization/modification/structure, target region and interaction network. Dynamic expression pattern of RNAs in human (or mouse) spermatogenesis and HSC lineage commitment is added. Sister Projects how many calories in one pringleWebIntroduction. Circular RNAs (circRNAs), a special class of endogenous noncoding RNAs, were identified in the early 1990s as transcripts and continued to be reported expressed in viruses, plants, archaea and animals. 1–3 Unlike linear RNAs, which are terminated with 5′ caps and 3′ tails, circRNAs present in a circular form whose 3′ head and 5′ tail ends … how many calories in one rasher of back baconWeb10 Dec 2013 · Circular RNAs are new players in regulation of post transcriptional gene expression. Animal genomes express many circular RNAs from diverse genomic locations. A recent study has validated a fairly large number of … how many calories in one raisinWeb11 Oct 2016 · circRNADb – A comprehensive database for human circular RNAs with protein-coding annotations in Databases October 11, 2016 7,673 Views It has been known that circular RNAs are widely expressed in human tissues and cells, and play important regulatory roles in physiological or pathological processes. high rise orlando