WebThe current standard of care for induction therapy in the treatment of acute myeloid leukemia (AML) consists of a “7 + 3” regimen, which includes 7 days of cytarabine 100 … WebAn increase of the hepatocellular lipid content ( Figure 2) is responsible for higher vulnerability. The higher vulnerability may, in particular during repeated chemotherapy, …

Unintended Hepatic Adverse Events Associated with Cancer …

WebSep 25, 2014 · Classes of chemotherapeutic agents. Cytotoxic chemotherapy agents exhibit their affects by interfering with DNA and RNA synthesis as well as cell division.2 These include alkylating agents, anti-metabolites, anti-tumor antibiotics, isomerase inhibitors, mitotic inhibitors. Also, advances in understanding cancer cell biology have led … WebOct 26, 2009 · Chemotherapy is meant to be toxic, but it is particularly aimed at the tumor cells. Collateral damage may occur to normal cells and tissues, especially if they are … date searching

Hepatotoxicity of Chemotherapy - ScienceDirect

WebDec 15, 2016 · This review is devoted to the actual for the present day problem of the hepatotoxicity of chemotherapeutic agents. Liver is the most important organ essential for the maintaining of the body’s ... WebChemotherapy is meant to be toxic, but it is particularly aimed at the tumor cells. Collateral damage may occur to normal cells and tissues, especially if they are fairly rapidly regenerating, as is the case for bone marrow cells, intestinal epithelial cells, and liver cells after hepatic injury. WebJul 8, 2014 · Antineoplastic therapy (chemotherapy) prolongs survival of patients with advanced and metastatic cancers. Since the liver has a rich … date search in google