WebDuloxetine, a potent reuptake inhibitor of serotonin (5-HT) and norepinephrine, is effective for the treatment of major depressive disorder, diabetic neuropathic pain, stress urinary incontinence, generalized anxiety disorder and fibromyalgia. Duloxetine achieves a maximum plasma concentration (C(ma … WebCymbalta (5.10). • Hyponatremia: Cases of hyponatremia have been reported (5.11). • Hepatic Insufficiency and Severe Renal Impairment: Should ordinarily not be administered to these patients (5.12). • Controlled Narrow-Angle Glaucoma: Use cautiously in these patients (5.12). • Glucose Control in Diabetes: In diabetic peripheral ...
End-stage renal disease - Symptoms and causes
WebDec 2, 2024 · What is Cymbalta? Cymbalta is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with … WebDose adjustments for duloxetine are not necessary for patients with mild or moderate renal impairment (CL(CR) > or =30 mL/min). For patients with ESRD or severe renal … hm satin top
Cymbalta and Dialysis disequilibrium syndrome, a phase IV …
WebRenal impairment . No dosage adjustment is necessary for patients with mild or moderate renal dysfunction (creatinine clearance 30 to 80 ml/min). Cymbalta must not be used in patients with severe renal impairment ... Cymbalta should not be used in the treatment of children and adolescents under the age of 18 years. Suicide-related behaviours ... Web• end-stage renal disease (ESRD): eCrCl, <10 mL/min.2 Overall, there is minimal informa-tion about the effects of renal disease on psychotropic therapy; our goal here is to summarize available data. We have cre-ated quick reference tables highlighting psychotropics that have renal dosing rec-ommendations based on manufacturers’ … WebSep 2, 2024 · Cymbalta (duloxetine) is a prescription drug for anxiety, pain from diabetic neuropathy, and other conditions. Learn about side effects, dosage, uses, and more. hm sat vu+