Chitinase-like protein 1
WebBackground: Chitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also called YKL-40 or human cartilage glycoprotein 39 (HCGP39), is a 39 kDa glycoprotein member of the glycosyl … WebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic acid to leucine in the chitinase-3-like catalytic domain. 27 The expression of YKL-40 was found in different mammalian organs and tissues (ie, ...
Chitinase-like protein 1
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WebSep 14, 2024 · Non-enzymatic chitinase-3 like-protein-1 (CHI3L1) belongs to glycoside hydrolase family 18. It binds to chitin, heparin, and hyaluronic acid, and is regulated by extracellular matrix changes ... WebChitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein member of the glycoside hydrolase 18 chitinase family that targets chitin but lacks enzymatic activity (Renkema et al., 1998). Although its physiologic function remains unknown, recent studies support a clear prognostic role for CHI3L1 in MS.
WebBackground and Objectives Multiple sclerosis (MS) is an autoimmune disease confined in the CNS, and its course is frequently subtle and variable. Therefore, predictive biomarkers are needed. In this scenario, we conducted a systematic review and meta-analysis to evaluate the reliability of chitinase 3–like 1 as a biomarker of MS. Methods Research … WebChitinase 3-like 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is strongly increased by various inflammatory and immunological conditions, including rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, and several cancers.
WebChitinase-3-like protein 1 (CHI3L1) is a secreted glycoprotein characterized by its ability to regulate multiple biological processes, such as the inflammatory response and gene transcriptional signaling activation. Abnormal CHI3L1 expression has been associated with multiple neurological disorders and serves as a biomarker for the early ... WebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic …
WebMar 21, 2024 · CHIT1 (Chitinase 1) is a Protein Coding gene. Diseases associated with CHIT1 include Chitotriosidase Deficiency and Gaucher's Disease.Among its related pathways are Digestion and absorption and Innate Immune System.Gene Ontology (GO) annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl …
WebChitinase domain-containing protein 1 (CHID1) is a highly conserved protein of unknown function located on the short (p) arm of chromosome 11 near the telomere. [5] The … ct taylor cleveland cavaliersWebJan 1, 2024 · Protein S100-A9, Protein S100-A8, Chitinase-3-like protein 1, Haptoglobin, Integrin beta-2, and Chloride intracellular channel protein 1 were more abundant in milk-derived EVs for clinical mastitis. The data obtained in this study expanded the repertoire of bovine milk-derived proteins and conduced more attention to the function. ct taylor constructionWebApr 4, 2024 · CHI3L1, chitinase 3 like 1 Vertebrate Orthologs 2 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog ... PR:000005423 chitinase-3 … ct tax websiteWebUrine chitinase 3-like. Background Acute kidney injury (AKI) is a frequently occurring syndrome in critically ill patients and is associated with worse outcomes. Biomarkers … ease hotelWebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and … ct taylorWebThe human homologue chitinase 3-like protein 1 was found to be more excreted in urine from septic patients with AKI than without. In summary, urinary chitinase 3-like protein 1 and -3 and acidic mammalian chitinase discriminated sepsis from sepsis-induced AKI in mice. Further studies of human chitinase proteins are likely to lead to additional ... ease hot flashesWebFeb 14, 2024 · NM_001374626.1 → NP_001361555.1 chitinase-3-like protein 1 isoform 2 precursor. Status: VALIDATED. Source sequence(s) AC137104 Consensus CDS CCDS87878.1 Related ENSMUSP00000119205.2, ENSMUST00000156873.8 Conserved Domains (1) summary cd02872 Location: 22 → 378 ct taylor construction ohio